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PDHK1(Phospho Thr338) Rabbit Polyclonal Antibody, 20ul[BT-AP11858] Adeno-associated Virus Packaging AKR/ZDHHC17 subfamily

SKU: 37672729481

4.1
SEK111.00 SEK153.00

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PDHK1(Phospho Thr338) Rabbit Polyclonal Antibody, 20ul[BT-AP11858] Adeno-associated Virus Packaging AKR/ZDHHC17 subfamilyPyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced

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Description

AKR/ZDHHC17 subfamily

Related pseudogenes have been identified on chromosomes 1 and 14

CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation

The protein encoded by this gene is closely related to STAM| an adaptor protein involved in the downstream signaling of cytokine receptors| both of which contain a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM)

Belongs to the synaptotagmin family

PDHK1(Phospho Thr338) Rabbit Polyclonal Antibody, 20ul[BT-AP11858] Adeno-associated Virus Packaging AKR/ZDHHC17 subfamilyPyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced

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