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LIF Polyclonal Antibody, 50ul Antibody Humanization The encoded protein| which is

SKU: 41135757902

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LIF Polyclonal Antibody, 50ul Antibody Humanization The encoded protein| which isLeukemia inhibitory factor encoded by LIF is a pleiotropic cytokine with roles in several different systems. It is involved in the induction of hematopoietic differentiation in normal and myeloid leukemia cells, induction of neuronal cell differentiation, regulator of mesenchymal to epithelial conversion during kidney development, and may also have a role in immune tolerance at the maternal fetal interface. Alternatively spliced transcript variants

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Description

The encoded protein| which is primarily cytosolic but can shuttle to the nucleus| also can interact with estrogen receptors alpha and beta and promote the proliferation of breast cancer| brain tumors| and lung cancer

Cell surface receptor for LCN2 (24p3) that plays a key role in iron homeostasis and transport

An important paralog of this gene is MYH1

pylori-associated gastric disease

MMP12 may play a role in aneurysm formation and mutations MMP12 are associated with lung function and chronic obstructive pulmonary disease (COPD)

LIF Polyclonal Antibody, 50ul Antibody Humanization The encoded protein| which isLeukemia inhibitory factor encoded by LIF is a pleiotropic cytokine with roles in several different systems. It is involved in the induction of hematopoietic differentiation in normal and myeloid leukemia cells, induction of neuronal cell differentiation, regulator of mesenchymal to epithelial conversion during kidney development, and may also have a role in immune tolerance at the maternal fetal interface. Alternatively spliced transcript variants

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