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NCoA-5 Polyclonal Antibody, 100ul Apoptosis & Autophagy Two alternatively spliced transcript variants

SKU: 58735043987

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NCoA-5 Polyclonal Antibody, 100ul Apoptosis & Autophagy Two alternatively spliced transcript variantsNCOA5 (nuclear receptor coactivator 5) encodes a coregulator for the alpha and beta estrogen receptors and the orphan nuclear receptor NR1D2. The protein localizes to the nucleus, and is thought to have both coactivator and corepressor functions. Its interaction with nuclear receptors is independent of the AF2 domain on the receptors, which is known to regulate interaction with other coreceptors. Two alternatively spliced transcript variants for this

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Description

Two alternatively spliced transcript variants

The transcription factor SOX-17 may act as a transcriptional regulator after forming a protein complex with other proteins

It interacts with CDC25 phosphatases

Gene Ontology (GO) annotations related to this gene include chromatin binding and transcription regulatory region sequence-specific DNA binding

Plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter

NCoA-5 Polyclonal Antibody, 100ul Apoptosis & Autophagy Two alternatively spliced transcript variantsNCOA5 (nuclear receptor coactivator 5) encodes a coregulator for the alpha and beta estrogen receptors and the orphan nuclear receptor NR1D2. The protein localizes to the nucleus, and is thought to have both coactivator and corepressor functions. Its interaction with nuclear receptors is independent of the AF2 domain on the receptors, which is known to regulate interaction with other coreceptors. Two alternatively spliced transcript variants for this

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