ENC1 Rabbit Polyclonal Antibody, 50ul Culture Plate Inserts a scavenger receptor protein that

a scavenger receptor protein that mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL)

Overexpression of this gene suppresses the activation of NF-kappa B induced by TNFRSF9 or TNF receptor-associated factor 2 (TRAF2)| which suggests that this protein is a negative regulator of TNFRSF9-mediated signaling cascades

and binds copper

brain and adrenal glands

This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment

ENC1 Rabbit Polyclonal Antibody, 50ul Culture Plate Inserts a scavenger receptor protein thatThis gene encodes a member of the kelch related family of actin binding proteins. The encoded protein plays a role in the oxidative stress response as a regulator of the transcription factor Nrf2 and expression of this gene may play a role in malignant transformation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.