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NAC3 Polyclonal Antibody, 50ul Mechanical Pipette inositol polyphosphate-5-phosphatase is involved in

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NAC3 Polyclonal Antibody, 50ul Mechanical Pipette inositol polyphosphate-5-phosphatase is involved inThis gene encodes a member of the sodium calcium exchanger integral membrane protein family. Na+ Ca2+ exchange proteins are involved in maintaining Ca2+ homeostasis in a wide variety of cell types. The protein is regulated by intracellular calcium ions and is found in both the plasma membrane and intracellular organellar membranes, where exchange of Na+ for Ca2+ occurs in an electrogenic manner. Alternative splicing has been observed for this gene and

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Description

inositol polyphosphate-5-phosphatase is involved in regulating membrane trafficking and is located in numerous subcellular locations including the trans-Golgi network

Serine palmitoyltransferase converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate and is the key enzyme in sphingolipid biosynthesis

Alternative translation initiation site usage results in the production of different isoforms (PMID:12105216)

Mutations in this gene have been associated with the hepatocerebral form of mitochondrial DNA depletion syndrome (MDDS)

including release of gastrointestinal hormones

NAC3 Polyclonal Antibody, 50ul Mechanical Pipette inositol polyphosphate-5-phosphatase is involved inThis gene encodes a member of the sodium calcium exchanger integral membrane protein family. Na+ Ca2+ exchange proteins are involved in maintaining Ca2+ homeostasis in a wide variety of cell types. The protein is regulated by intracellular calcium ions and is found in both the plasma membrane and intracellular organellar membranes, where exchange of Na+ for Ca2+ occurs in an electrogenic manner. Alternative splicing has been observed for this gene and

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