MCLN2 Rabbit Polyclonal Antibody, 50ul Biomatrix transcription regulation

transcription regulation

Expression of this protein was reduced in human breast cancers while its overexpression reduced tumor growth and metastasis

Mutations in this gene are a cause of colorectal cancer (CRC)

Chloride channel 4 has an evolutionary conserved CpG island and is conserved in both mouse and hamster

The TRRAP/TIP60 complex acetylates nucleosomal histones important for transcriptional regulation

MCLN2 Rabbit Polyclonal Antibody, 50ul Biomatrix transcription regulationMucolipins constitute a family of cation channel proteins with homology to the transient receptor potential superfamily. In mammals the mucolipin family includes 3 members MCOLN1 (MIM 605248) MCOLN2 and MCOLN3 (MIM 607400) that exhibit a common 6 membrane spanning topology. Homologs of mammalian mucolipins exist in Drosophila and C. elegans. Mutations in the human MCOLN1 gene cause mucolipodosis IV (MIM 262650) (Karacsonyi et al. 2007